Zesty Paws Multi-Collagen Bites is the most complete collagen chew we reviewed — dual bovine + marine collagen peptides plus eggshell membrane, cod liver oil, hyaluronic acid and vitamin C, in a soft chew dogs eat like treats. The trade-offs are chew-format dosing precision and absorption, and marine/bovine sourcing to check against allergies.
What the current label lists
| Active | Per serving |
|---|---|
| Collagen peptides (bovine) | 1000 mg |
| Collagen peptides (marine) | 400 mg |
| Eggshell membrane | 200 mg |
| Cod liver oil | 200 mg |
| Hyaluronic acid | 40 mg |
| Vitamin C (ascorbic acid) | listed |
Strengths
- Dual bovine + marine collagen, both named and dosed
- Eggshell membrane, cod liver oil, HA and vitamin C add joint and skin support
- Highly palatable soft chew; NASC-certified
- Widely available and often discounted
Limitations
- Chew format = lower dosing precision and absorption than a liquid
- Contains marine and bovine plus chicken flavor — check allergy history
- No studied UC-II dose (uses hydrolyzed peptides)
| Active ingredient | Per 2 mL |
|---|---|
| Hydrolyzed collagen peptides (Type I & III) | 462 mg |
| Undenatured type II collagen (UC-II) | 48 mg |
| Micro-emulsified salmon oil (omega-3 EPA/DHA) | ~126 mg |
| Pork bone broth concentrate | ~126 mg |
| MSM (methylsulfonylmethane) | ~63 mg |
| L-glutamine | ~52 mg |
| Tyndallized S. boulardii postbiotic | ~21 mg |
| Low-molecular-weight hyaluronic acid | ~8.4 mg |
| Vitamin C (sodium ascorbate) | ~4.2 mg |
| Ginger root extract | ~4.2 mg |
| Natural astaxanthin | ~0.5 mg |
Manufacturer-published formulation, current as of July 2026, per 2 mL daily serving. Ingredient amounts describe the contents; the individual actives have published evidence (below), but this exact multi-active blend has not been tested as a finished product in a controlled canine trial. Introduce gradually and check with your vet if your dog has kidney disease or a protein-restricted diet.
Frequently asked questions
Is Zesty Paws Multi-Collagen good for dogs?
Does Zesty Paws collagen have UC-II?
Is Zesty Paws collagen safe for allergic dogs?
Sources
- Gupta RC, Canerdy TD, Lindley J, et al. Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate. Journal of Animal Physiology and Animal Nutrition. 2012;96(5):770–777. doi:10.1111/j.1439-0396.2011.01166.x
- Dobenecker B, Böswald LF, Reese S, et al. The oral intake of specific bioactive collagen peptides improves gait and quality of life in canine osteoarthritis patients. PLoS One. 2024;19(9):e0308378. doi:10.1371/journal.pone.0308378
- Roush JK, Dodd CE, Fritsch DA, et al. Multicenter veterinary practice assessment of the effects of omega-3 fatty acids on osteoarthritis in dogs. JAVMA. 2010;236(1):59–66. doi:10.2460/javma.236.1.59